The Reverse Mullet Healthcare Podcast

The Science of Cellular Rejuvenation Through Fasting-Mimicking Diets with Dr. Joseph Antoun

• BP2 Health

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Are we approaching fasting all wrong? In this fascinating conversation with Dr. Joseph Antoun, MD-PhD and CEO of L-Nutra, we dive deep into the science of cellular rejuvenation through fasting-mimicking diets—a revolutionary approach backed by research from 18 universities including Harvard, Stanford, and Mayo Clinic.

Dr. Antoun challenges conventional wisdom about intermittent fasting, explaining why skipping breakfast might actually work against longevity goals. Instead, he advocates for "front-loading" your fasting period—finishing dinner by 7pm and eating breakfast the next morning—to align with your body's natural hormonal rhythms and metabolic needs.

The true magic happens when we explore ProLon, L-Nutra's pioneering 5-day fasting-mimicking food program. Unlike traditional fasting, this scientifically formulated nutrition plan keeps you eating while your body enters a deep fasting state, triggering cellular "autophagy"—the Nobel Prize-winning self-cleaning and rejuvenation process that starts around day three. Research published in Nature shows three cycles can reverse biological age by 2.5 years.

Perhaps most groundbreaking is the application for chronic disease management through the new L-Nutra Health platform. Clinical trials demonstrate two-thirds of diabetes patients reduced medication within six months of following their protocol—just five days monthly of specialized nutrition with physician and dietician support. Health economic studies show insurers break even in just ten months, creating a rare alignment between patient outcomes and financial incentives.

Whether you're seeking longevity, weight management, or a science-based approach to metabolic health, this conversation illuminates how precisely formulated nutrition can activate your body's innate healing mechanisms—potentially changing your relationship with food, fasting, and cellular aging.

Justin Politti:

Welcome to the Reverse Mullet Healthcare Podcast by BP2 Health. We are here at ACLM Conference in Orlando 2024. I'm Justin Politti. I'm Dave Pavlik.

Ellen Brown:

I'm Ellen Brown and I know it's hard for those of you watching live or the recorded video version that Justin's hard to recognize because he has sunglasses and the mullet wig on. So if you didn't recognize Justin, it's the real Justin, the real deal. Yeah, but we're here with a special guest, so tell us about yourself.

Joseph Antoun:

Hey everyone, this is Dr Joseph Antoun. Thanks for having me here today. Yeah, thanks for being here. Hopefully we're going to change somebody's life. I always wish that in my podcast.

Ellen Brown:

So I'm super pumped that you're here. See, dave and Justin don't even know I'm always pulling stuff out, but in my journey of learning really deeply about health at a different level, walter Longo's work was very instrumental. It was like the Zach Bush on the soil side and Walter on the longevity side and it was like this whole sort of trifecta ritual with all of his podcast guests.

Justin Politti:

There's a lot of inside baseball going on on that side of the table. Yeah, it's my job.

Ellen Brown:

But and so a number of fact. I will take a picture and I'll send it to my girlfriend. So a number of my friends have utilized Prolon and I want to hear about your new product today but have used Prolon for health reasons, not to try to lose weight, but truly for cellular restoration and autophagy and all the things that Prolon does, and so I feel like I have like a legend in here talking to you live at the Lifestyle Medicine Conference.

Joseph Antoun:

I feel useless because you know it better than I do.

Ellen Brown:

No, no, no, no, no. I, I just, wanted to share that because I think sometimes when somebody comes on the podcast and talks about a product or an intervention, sometimes immediately people are like, oh, it's something somebody's trying to tell me. But you guys really are a pioneer in a different type of intervention than most.

Joseph Antoun:

Thank you very much, and I did promise we're going to change somebody's life and we will. Through this next 20 minutes we're going to talk about this Quick introduction. My name is Joseph Anton. I'm an MD-PhD. I wanted to cure patients.

Joseph Antoun:

This is why I went to med school and then I discovered like most of you probably learned at some point, that we're taught to give a lot of pills. First we practice sick care, because we meet people after they're sick, not before, and then we give them a bunch of four or five pills. And I used to tease my attendee. I would say, hey, what is the expiry date of the prescription? I used to tease them at the hospital. There's no expiry. They have to refill it every month. They say, yeah, for the rest of their lives. Yes, refill it every month. They say, yeah, For the rest of their lives. Yes, and maybe we're going to add to this right.

Joseph Antoun:

And so I rebelled against that system. I went into first. I thought I'll do prevention. So I did health policy and public health and figured out that most people know already. Prevention they should eat healthy exercise. There was no new news. As we say, and you're always competing with the product, right, Should I go to the gym or should I sit in front of Netflix? Should I eat a plant-based or? This burger looks good, right.

Justin Politti:

Choices.

Joseph Antoun:

It's choices, but the product is the bad product and it's against choices. And I was like, why don't we come up with a product that is healthy, that is preventative, that is going to help people and compete product to product? And so I looked for what people do every day and it's food Eat every day of your life three to five times. And we decided to turn food as an asset of longevity, because we know people will comply. They eat food every day, the day they're born to the day they die. It's unfortunate that this trillion, multi-trillion dollar industry is governed by marketing and by theories and not true science. So we gathered a team of scientists.

Joseph Antoun:

Our founder you mentioned his name, Dr Walter Longo is probably the leading expert in longevity around the world. We gathered 18 universities behind us Harvard, USC, Stanford, Mayo Clinic and we started doing developing food formulations as we develop drugs, mice trials and then human trials in order to prove what we have that is going to bring. Food is longevity and food is medicine. So, after 23 years of research, we have developed two platforms of nutrition technologies. These technologies are essential for longevity or for for medicine. In the main one and you mentioned the main pro one our main discovery is what we call a fasting, mimicking nutrition, a five-day food that we give to you it's a very precise formulation that we ship it to your house. You open the box there's five days of food and you eat it over five days. Your body doesn't know you're eating, so it's called a fasting, mimicking nutrition.

Ellen Brown:

Oh, but you do know it when you do it. Yes, you do feel it I will get texts from somebody and go.

Joseph Antoun:

I'm on day three of Prolong. Yes, you're going to feel it and the concept is when the body thinks you're not eating, of course you're losing a lot of weight, which a lot of people love, but that's not the main concept. The main concept is the body on the first two days has a lot of reserve fat and glycogen. You consume those, right. It's like if you run a company, you don't have funding. You go to your bank and you use your savings and check in a car when you consume your bank account. So you're on day three of fasting and you're in a crisis. Say, you have a company and you spend your money. You're in a crisis mode. You go and you restructure the company. You start fixing. It's like, okay, I'm not doing well because my sales department, my marketing department, my supply chain. So the buddy on day three tells the cells we're in a crisis, you got to fix yourself.

Joseph Antoun:

Every cell goes through this process called cellular rejuvenation. In science we call it autophagy, self-eat, self-rejuvenate, and it won the Nobel Prize in Medicine in 2016. It's a big big thing. Now. It's just we know autophagy, what it does to the body, which is reverse, the bio-age, but we never had a product. So that process of autophagy, which again won that Nobel Prize in Medicine in 2016, is pushing every cell of the body to clean, detox, fix the inside, rejuvenate and again, I always compare it to a company trying to restructure. Whatever is going wrong, we try to fix it and for the first time now we, as humans, we have a technology in nutrition called Prolon or the fasting mimicking diet. This is the core technology that we sell to help you eat three to five days and benefits from the cell rejuvenation, so you can. Why we want to help you eat three to five days in benefits from the standard of rejuvenation, so you can. Why we want to rejuvenate cells.

Joseph Antoun:

The goal is to really, a little bit, take your biological age backwards. We want you and I always use this expression, we want you to be younger than your age. Why is that so? 90% of us will die out of four health conditions that all age-related diabetes, type 2, alzheimer's, cardiovascular and cancer. Right, you're not going to get Alzheimer's at age 20, you're going to get first heart attack at age 30, et cetera, et cetera. So the goal is to keep your cells younger than your coach. And that's true prevention, because we're giving you, hopefully, extra the chance. We cannot promise people are going to get longer, but we're giving them best chances for their cells to stay younger than their age and a little bit away from the onset of chronic conditions.

Joseph Antoun:

So that ProLon for promoting longevity is a consumer product. You buy it, you do it three times per year. You only need to do it three times per year. It's five days, three times per year. You're only doing 15 times 15 days per year. Anyone can do it 365 days. We priced it exactly as the price of food for five days, so at $175,. The average American food, beverage and supplement spends around that number within five days. So it's a cost neutral. I really emphasize this because people should do ProLon three times per year. I haven't seen any product that can reduce the cells, help you lose the weight and help a lot of people. So that's the concept for longevity. The sales help you lose the weight and help a lot of people. So that's the concept for longevity.

Joseph Antoun:

The second concept same fascinating technology. We said okay, wait a second. So you're running a company. You're now have no revenues, no funds. You're going to restructure, you're going to fix If you know that I don't have revenues because my sales team is not doing a great job. You start fixing there, right, right. So what we learned is that if you have diabetes, for example, if you have cancer, if you have all that, the body is saying okay, I know what's going wrong, let me try to fix. And we started with diabetes. We've done a lot of trials on diabetes and what we're saying is that patients taking the fasting-mimicking diet within six months so this is just five days a month, every month because you have a health condition, you do it every month, once a month. Within six months, two thirds of them are dropping one pill.

Ellen Brown:

And it's ketosis Like. When you were talking about this, I was like right, bingo, ketosis, right. One of the most effective insulin resistant reversal tools is ketosis, which Proline does a beautiful job of putting you into ketosis. I mean it's far more than that. You're like please stop.

Justin Politti:

But what's the benefit for somebody not like me and I'm not on the inside, but I've done intermittent fasting. What's the difference? In wide intervals? How is this better than doing it without consuming Prolon?

Joseph Antoun:

Two fantastic questions. Quickly answer the ketosis. The ketosis is the metabolic low-carb stage, but again there's a cellular rejuvenation. Yes, so diabetes has three root causes and I love when you and I were chatting before you said root cause right why medicines fail in diabetes or why even ketogenic diet In the long term they do fail in diabetes.

Joseph Antoun:

Yep, because they all treat one root cause, which is insulin resistance High carb, high fat, insulin resistance. But diabetes has two other root causes. The second one is muscle loss right, because if you maintain high muscle, you're burning the carbs. Number three is very important is aging. We, the four of us, maybe we had the same actually, maybe we're eating bigger volumes of food 15 years ago and we're skinnier, right? So aging is behind. If you eat bad at age 27, you burn it. If you eat bad at age 27, right?

Ellen Brown:

you burn it. Yeah, it's bad at age 55. There's a lot more grease in your 20s, so yes, remember blood sugar, insulin resistance and and fat this.

Joseph Antoun:

Yes, drugs do that, glp1 do that, ketosis do that. But but they're not enough is muscle. Keep the muscle high to burn the carbs and age it. And this is why the fasting-inducing diet is hidden all through your conscience. Rejuvenate the age of the cells. You're biologically younger. You're not 27 chronologically, but you're close to it biologically. Your cells can burn, your muscle is active and muscle protection, your muscle protects with the fasting.

Ellen Brown:

Yeah, absolutely. So that's the big. So now Justin's question about how this is different than just doing intermittent fasting.

Joseph Antoun:

So, justin, when you do intermittent fasting, say you're skipping breakfast and delaying a little bit too much. I don't know if you do the 16-hour or the 18-hour 24-hour. It has to be 23 and a half, because you're eating.

Ellen Brown:

That's a true fast 24, yep what?

Justin Politti:

you're doing is called OMAD.

Joseph Antoun:

Omad, the one meal a day, yep, what you're doing, yep, which is very bad for longevity. There you go and I'll tell you why. And I'll tell you why. We studied the first 13 years before we developed the fasting. We were a water fasting, so we studied the entire fasting science. It's coming from Walter Longo. It is.

Joseph Antoun:

We started as Waterfast, so we were a proponent and then, when it failed at some certain point, we developed the nutrition. It's actually the National Institute of Health that gave us funds to develop a fasting community. It wasn't either a business project or anything. We were studying fasting. So I'll tell you a little bit about the trick.

Joseph Antoun:

So when you wake up in the morning is when you're thinking. Your brain needs the most calories because you're thinking, you're going to work, you're walking, you're exercising, if you go to the gym, etc. This is the need to have calories and with intermittent fasting, you're starving the body when the need is there. That's why in the afternoon you start feeling weak a little bit or dizzy, but you're starving the body when it doesn't eat. Then you go and you eat.

Joseph Antoun:

Evening time when you go back from work, right, and evening time when you eat you're going after that to sleep, right, and when you sleep is is the least need for calories. So what the body says is like okay, I just got a bunch of calories, her brain is struggling, the kidneys are, so the essential organs have been struggling for 14 hours and now I got a calories. Let me talk about right, the it's. It's the concept of binge eating. And then I I will start, I'm sleeping, I'm not burning that. So when you eat a lot in the evening time, say at four, five, six, seven, your insulin spikes and your igf spikes, so these are anabolic there, and when you sleep you're anabolic, meaning you retain what you eat so you're giving the calories when the body is in storage mode, rather than the body is in the catabolic and it's spending.

Joseph Antoun:

So what happens? You do it Now. If you're starting by being very obese or carrying overweight, you have high blood sugar. It helps some people because it's still starving. It's starving what you don't want to starve, which is the essential organ, and it's feeding fat. But still it's better than eating bad all day.

Ellen Brown:

Right or eating too much.

Joseph Antoun:

Overall, yeah, some people say I do OMAD, I do 16 hours. It helped me. Of course it's going to help you, because if you're overweight or if you had a very bad diet, it will help. But what I'm trying to say is you got to do it in transition and then you got to move to a better state. Better state is eat in the morning, eat a light dinner, sleep on a little bit empty stomach At night. You're not storing the excess fat and when you wake up in the morning you're catabolic. You're spending Whatever you eat. You spend your little. When you sleep, the hormones of storage are up, so you're doing 12 to 14 hours of fasting, but they actually start. We call it front-ended. They start at 7 pm, don't eat after 7, and then eat the next day at 9. You did 14 hours, but you did it exactly when the body doesn't need the food and is trying to store. On an empty stomach doesn't store and the next day, whatever you eat, you spend it. That's the better way of doing the intermittent fasting.

Ellen Brown:

So tell us. I have two questions. So one, the fast mimicking diet, the FMD. I want to talk a little bit more about the science of that versus intermittent fasting right, and I know you're hitting on that. But this idea, because to me, the reality, so like when you do Prolon, because I don't think you guys have done it before you know well you talk about I'm not going to steal the thunder, but you'll explain the product, but it's. It is very much like you're getting little bursts of food throughout the day and they're very specific in their dietary, you know contents to again put your body into a certain state of ketosis, but also to that cellular, you know, to autophagy, right. But what I was going to ask is tell us to this new diabetic intervention that you all have created and launching, which is, I think, l-neutral health right.

Ellen Brown:

Because I think everybody knows L-neutral for Prolon. But now you've got L-neutral health and I'm also wondering I'm going to see if I how many questions you can remember at once is does that allow you to go from being just a consumer product to be a B2C through medical prescriptions? Right now, all of a sudden, you can help people from an access, because right now, if you don't have the cash to pay $175 for Prolon, you don't get it. So does this also put you all in a position where now, if you're getting a prescription for food, you can actually seek the L-Nutra Health version? All that and you had a question.

Justin Politti:

Well, so I did the Peter Atiyah fasting app for a long time. I don't do it, yeah, zero. I don't do it anymore and I have a broader eating window now than I did when I first started. So I've modified. But my question was on that app, you can't get into ketosis at 14 hours, like you've got to go much longer.

Ellen Brown:

Right, which is why it's five days.

Justin Politti:

Yeah, like you've got to go much longer, right which?

Ellen Brown:

is why it's five days. Yeah well, so I guess are you?

Justin Politti:

how does that work? Like getting into ketosis in the eating period of time that the window that you have and peter left the app and it actually changed his mind.

Joseph Antoun:

I don't know, yeah, that's a whole interesting story this is where we go, because he read our science right this is where we go back is is we've had enough of books and theories, just read the science, and the science is clear, and so I'm going to close the intermittent fasting question, to close that chatter and go back to diabetes. So it's not to get to any ketosis, because you both are hitting on ketosis. There's a shallow ketosis that most people get into when you do intermittent fasting, when you do a ketogenic diet right. But it's a shallow ketosis, right. Fasting is a deep ketosis and what you need you need to go deep to help the cells rejuvenate exactly so the biggest difference between to answer your questions is, if you skip a meal, you're not going to rejuvenate the cells you're going to just say okay, let's go back to the company example, like okay, you know I need a million dollar to operate my company.

Joseph Antoun:

I need 2,000 calories to operate in my body. You give me the check, four hours late I have some checking as I come.

Joseph Antoun:

So you're saying, okay, I have a little bit of fat, you can have a lot of it, but you lose a little bit of glycogen, you're done, you don't need to go, you don't get into crisis. So the big difference between a five-day prolonged fasting versus the intermittent fasting is the crisis Got you. Prolongon induces a deep fast and a crisis so that the cells rejuvenate and heal and hopefully give you a very good path to longevity. Intermittent fasting helps you, on a shorter, on a shorter, to lose some weight, balance your metabolism. But then you got to do it right. You got to do the front end stop dinner early and still have your breakfast. Breakfast is, I mean, there's a big battle, oh, but breakfast and and and. Again it's marketing dominating the breakfast and there's many articles showing not the most important meal of the day it is, it is it is you should do.

Joseph Antoun:

You should eat breakfast, but you should still do fasting. Like, how am I going to do fasting? It's because it's dinner. Get your dinner early, seven o'clock, even if you eat your breakfast at eight, nine or ten. You already did 14 hours of fasting. That's already incredible. This is the best. I always tell people that if you want to do something right for longevity, sleep a little bit hungry or sleep a little bit of it, which is the most difficult things to do in our life.

Joseph Antoun:

Most people are obese, have 60 diets and counseling and, if you go deep, deep, they're stressed eating at night because they're finishing their late their work because they're stressed, and they're at work because they're sitting in front of a movie with their significant other and they're snacking.

Ellen Brown:

It goes back to the whole concept of satiety. I think we just have completely lost touch with even talking about it. And when you introduce that concept it's like, oh yeah, if I eat to feel satisfied, change is the game.

Joseph Antoun:

Yeah, and when you eat late at night, because it matches our lifestyle and our stress and our staying late now with the movies and the work, they say oh, it's easy for me to intermittent fast because I'm not hungry in the morning. Of course you're not hungry. You ate late at night. You had reflux, so your throat is a little bit burning. You don't have appetite in the morning, so intermittent fasting took off by skipping breakfast because it was the easy thing to do, but it's the wrong thing to do from a longevity perspective.

Justin Politti:

Yeah, so you're saying go to bed a little bit hungry too. You said that a couple of times. Is there anything related to like portion control and what you're consuming, like throughout the window Of?

Joseph Antoun:

course. So in the past we used to say one calorie in, one calorie out. Sorry, it's not perfectly right, but it matters. Obviously, if you eat a lot of calories, you're going to have to play with timing and exercise to burn it, but it's not always. Actually, what we're saying is to prove that one calorie in at night is going to be stored. One calorie when you're working throughout the day is going to go to the path of utility, right, yeah, yeah, because hormonally, when you sleep, your growth hormone is up, insulin and morning are up, so you want to store. During the day you want to spend, so there's differential use of calories. It's not equal. But of course you don't want to eat a lot and you can assume you're going to lose weight regardless if you do.

Ellen Brown:

In terms of this, so wait, before you jump into the other day thoughts comments, because I know this is like we're getting into the territory that you guys rib me on all the time. Rib you. Yeah, you guys rib me. It's cool. It's cool about the wearables. I'm the weird sister, no no. I'm going to go look it up, ProLon, because I'm interested. I should have brought the box I actually have a ProLon at home that I haven't put at home.

Joseph Antoun:

Something I'd like to try. Yeah, to conclude and simplify, because we're getting to some. For some people it sometimes gets confusing. Remember, fasting is good when done right, which is an early dinner, and still have your breakfast. So you're doing that 12 to 14 hours. We call it circadian fast and there's a lot more to it, meaning the sun is down, you're stopping to eat. You're sleeping well at night, because when you eat late and you sleep, you don't sleep well.

Joseph Antoun:

Right, you have your nightmare because your body is working while your brain is trying to sleep. We don't realize that your body is working right. There's digestion. You don't feel it because you don't have a sensory or nervous system, but it's working. So the brain cannot sleep, so it actually impacts your sleep. It impacts your energy. The next day you spend less time, calories, you exercise less, you pick up more weight. And this is where a lot of intermittent fasters. They end up saying it helped me a little bit, because the first 5% is easy to use, and then I got stuck and then I stopped that's the story of 90% of it and do it right. It just keeps helping you. So circadian fasting when the sun is down, have your last meal, get your breakfast. You wake up. Believe me, hungry. Everyone tells me and I used to be that I wake up. I'm not hungry. This is why I do You'll be hungry if you don't eat, you'll wake up hungry and you want to eat.

Joseph Antoun:

And you'll see your body going perfect. It's not just eating, it's sleeping at night. It's like the biology of rejuvenating the organs Instead of having them work at night, they'll sleep at night, they'll rejuvenate. So it's five days, the main goal why to go fight? It's food, but precisely formulated to keep you in a fasting state, in a true fast, not a ketosis, a true fast, and the goal is to rejuvenate yourself so that you live a healthier and better life. We just published in Nature, six months ago Nature is the number one science journal of the world. We just published an article showing if you do three prologues, you're reversing your bio-age score by 2.5 years. If you do it three times per year, every year between age 50 and 70, it's 11 years of bio-age. This is big. We're not promising people they can live 11 years, but we're saying we're the age of the cells. You might die from an accident, you might still develop a cancer, but we're saying from an age correlated health conditions, the four big killers.

Justin Politti:

We're giving you a better chance to keep them so you use the term true fasting versus fasting, which my night, well, I always thought fasting was just water or maybe some coffee without anything else in it. So you know, for a little bit of caffeine, but what? What is a true fast versus what I'm doing? What I did, yeah, so what?

Joseph Antoun:

you what? What you do, which is non-ingestion of food, is a true fast, versus what I'm doing or what I did. Yeah, so what you do, which is non-ingestion of food, is a true fast. What we do is fasting with food, is what we call a physiological fast. So we developed a nutrition formulation that we looked at the cells, at the radars, the radars of the cell, how the cell detects food. There are three radars sitting on the cell that detects food. We call them nutrient sensing pathways. So we studied them the PKA, the TOR and the RAS pathway and we figured out a formulation that doesn't over-trigger the pathway.

Joseph Antoun:

So the cell is getting fed without recognizing that it's getting fed. This is why it's called a fasting-mimicking diet, physiological fast not a true fast, but it's a big discovery. So we have now 134 patents on it and 40 clinical trials. It's a physiological trial, gotcha, but it makes fasting healthy, because you don't want to go on a water fast. Why we developed it? Because when we learned that to rejuvenate the cells you need at least three days, nobody wants to water fast for three days. Actually, you can faint, you can feel weak.

Joseph Antoun:

So it came out of necessity. You can't work out very well. At the end of the day, you cannot go to work, yeah. So this is why it's the US, it's the taxpayers, that actually came to us to develop us and USC to develop the fasting. It was out of necessity to have people cross a long fast to benefit themselves without feeling so hungry or so weak.

Ellen Brown:

And, by the way, you're not supposed to work out hard when you do ProLine, so it is.

Justin Politti:

That I don't like.

Ellen Brown:

That has supposed to work out hard when you do pro line, so it is that has been a barrier that has been a barrier for me in the past of doing it, because it's like, no, I'm somewhere and I want to be able to go ride my bike or run or whatever, and I don't want to take five days to not you know, but you take a week off of exercise while you're doing this is that the suggestion no, you can.

Joseph Antoun:

You can do your weight lifting, you do your pilates, your yoga, but don't run like a marathon.

Justin Politti:

All right, so I could do my HIIT classes or whatever.

Ellen Brown:

That might be kind of like running a marathon.

Joseph Antoun:

It's a little different, just think that you're getting half of the calories that you would typically get, so you've got to adjust to that.

Justin Politti:

I'm not sure if you're doing damage or basically undoing what you're trying to do while you're working out too hard.

Joseph Antoun:

You're not undoing but you're getting yourself. If you spend a lot of calories, you're taking the risk of hyperglycemia, because if you want, you don't want to overspend Diabetes.

Ellen Brown:

Alnutra.

Joseph Antoun:

Health no passing out. You said something you said for those who cannot pay the $175, maybe the medical program gets.

Ellen Brown:

I was just curious, it's my hypothesis, hypothesis.

Joseph Antoun:

It's one of my biggest fights today. The 175 dollars right, because we priced it to be neutral. That people always think oh, they go to the website, they go to prolo and my first they say, okay, should I pay 175 or not? The studies show that the average us citizen spends on food, so beverage and supplement let me be clear.

Ellen Brown:

I'm talking about the med five days. I'm talking about the Medicaid population. So I'm talking about those that are below the federal poverty level, that maybe they're on SNAP, maybe they're on. So there is. I don't want to say they're necessarily food insecure, but they're in that.

Justin Politti:

Does HSA cover this right? Prolon HSA FSA yes, okay.

Joseph Antoun:

Sorry, I just wanted to clarify that because that's also the perception. When people come and buy food from from us, prolon or the others, they're thinking sometimes they think it's a cost. We actually price them to swap the cost of whatever they would buy. Yeah, so in the us, when you know we're in la la, is even more expensive. The average person spends 200 on food and beverage and we per week.

Ellen Brown:

And what's the new store? Air One, the new fancy store in LA, air One.

Joseph Antoun:

Yeah, At Air One you spend $1,000.

Ellen Brown:

Exactly.

Joseph Antoun:

I'm just trying to say that when somebody goes to buy Prolon, keep in mind that you don't need to buy other foods for the five days. It's just, instead of going to Whole Foods, paying Whole Foods whatever, you pay for five days, you just buy it's your meal for the week.

Justin Politti:

It's a swap of the cost.

Joseph Antoun:

Now I'm very passionate to help the Medicaid patients and the poor patients. By the way, even today, if they contact us and they want a heavy discount, we do that. Okay, we're very passionate. Our founder, professor Walter Longo, that you mentioned he actually donates 100% of his shares to the CreateCruiseFund mission. We're a company with a mission. We're not here to just generate profits. No, we're a company driven by MD, phds, doctors and PhDs and a big mission goal of changing people's lives. So we will not say no, even if I have to give it for free for a patient, I will do that for a patient. As a CEO, I'm 100% behind that. What we did with doctors. So we have over 12,000 doctors in the US registered with us. So when a doctor because mostly Medicaid patients or, unfortunately, the lower the income, the higher correlation of having a health condition.

Ellen Brown:

Oh, absolutely.

Joseph Antoun:

So through doctors, we actually, if you go to a doctor and you get a code with ProLon, you're getting the box for $130 to $150, depending on how many good, which is cheaper. If you divide that by 15 meals, five days, three meals a day, it's $5 to $7 a day, which is what even a Medicaid patient would spend on a burger and or on whatever food they give them. Even for that, but our goal ultimately is reimbursement. So we just launched you talked about diabetes we just launched a big program called L-Neutral Health. L-l is longevity dash, neutral longevity through nutrition L-NeutralHealthcom. And the program is called Diabetes Regression and Remission. So it's the five days. Like Polon, it's the five-day fasting and vegan diet, but we have a dietician supervision and a doctor supervision, so it's a full program. And what we help people with patients with diabetes or pre-diabetes or blood pressure, any metabolic condition, we help them do five days a month over six months and then to maintain the benefits, it's a quarter after that. Okay, what we're showing and this is the first time in history of medicine two-thirds of the patients within six months, two-thirds will drop the dose of their medication or will drop a full meditation, two-thirds. And then we're showing that if on average, it seems every six months, when we say six months, it's just five days a month. We're not talking about change your lifestyle. Eat healthy. There's no eat healthy or exercise in between, nothing, just five days a month. And we have two trials. Now we did another trial for 12 months and it's showing similar results. You're decreasing insulin, you're decreasing blood sugar, you're decreasing Hb1c and you decrease the need of diabetes. So ACLM, the Association of Lifestyle Medicine, the American College of Lifestyle Medicine, the Endocrine Society and the American Dietetic Association, they got together and they created a claim for us called diabetes regression going backwards, and diabetes remission meaning you read no more medication because diabetes treatment and cure is an FDA approved pharma claim.

Joseph Antoun:

Diabetes regression and remission is for programs like ourselves, because diabetes treatment and cure is an FDA-approved pharmacling. Diabetes regression and remission is for programs like ourselves, where we apply nutritional intervention to regress the patient or to take them off medication. We call it regression and remission and the program is just $250 a month. Again, $250 is not an extra cost. We're swapping your food and we're giving you a dietician and a physician for only $250.

Joseph Antoun:

Is taking patients off medication we just published last week in Value in Health For everyone listening to us today who works at a hospital or health system or insurance we just published an article in Value in Health, which is a top health economic journal it's the official journal of Hisport showing that if a payer pays $250 to $350, even per month, on the diabetes program, they will break even on month 10. So within the first year, if a hospital, if a health system, if an insurer pays $4,000 and even more than $250 for our program, they will break even on month 10 because their savings on their medication and their saving on complication there's no programs that you can save costs on the chronic disease.

Ellen Brown:

So, based on all the work that we do in value-based care on a medicare advantage population, I would argue that if you are, if you are regressing and remitting diabetes, from the research we we have in the data we have, you would be looking at somebody who's costing about their about, let's say it's about 25 000 a year in costs. When that gets remitted you drop in half, so that's a 4x return. So if somebody's spending, you know, three thousand dollars a year on your program but they're saying twelve thousand dollars a year in cost, that's a 4x return for that payer that's investing in your program within the same year.

Joseph Antoun:

You cannot reverse all the side effects no, no it's a tema, but after we studied, that's what I'm talking about we. We showed 44 000 ultimate investment easy 44 000 on a payer that a lot of players say, hey, I had no patients for two and a half to four years. I could, so it was so important to show savings in year one. Absolutely Every insurance, every pay one day on year one.

Joseph Antoun:

And this is the first time your patient is going backwards rather than forwards. So you're hitting that your doctor is so happy their patient is getting year limit and reverse and the period is happy. It's the first time we aligned all three in America and we're doing the right thing. It's a metabolic disease. You treat it with the true, I mean think about it.

Justin Politti:

It's a real cause.

Joseph Antoun:

It takes me 30 minutes to explain it all the time, and then one sentence summarizes it right you overeat, you age, you become diabetic. How you can reverse the fastest and overeating status? That's why we're making fasting is the fastest way.

Ellen Brown:

It is. It is, it is, and it's a lot less expensive than glyphs. So anyways, well, yeah you guys have any questions?

Justin Politti:

no, I don't try that. So how do I?

Ellen Brown:

get my hands on some prolon, yeah, yeah I think, I think you can be helped over here how you can get your hands on some prolon.

Joseph Antoun:

So for everyone who wants to just do it, for weight and longevity and cellular rejuvenation, do it three times per year. Prolonlifecom For those that are interested in pre-diabetes, diabetes or other metabolic conditions. Healthutrahealthcom is the way you can find the support there Outstanding Well.

Justin Politti:

Thanks for joining us. It was super fun. Thank you Appreciate it.

Ellen Brown:

All right, take care. Thank you very much.